职称 教授

学位 博士

政治面貌 中共党员

电话 13100713659

邮箱 xueqinliu@mail.hzau.edu.cn

研究方向 水产病毒免疫致病机理及综合防控

 教育经历 

2003/09-2006/06 必威BETWAY官网，动物医学院，博士

1998/09-2001/06  必威BETWAY官网，动物科技学院，硕士

1994/09-1998/06  必威BETWAY官网，动物科技学院，学士

 主要职历 

2017/01-至今，  必威BETWAY官网，必威BETWAY官网，教授

2010/01-2016/12  必威BETWAY官网，必威BETWAY官网，副教授

2013/02-2014/02  美国佐治亚大学，兽医学院访问学者

2007/03-2008/05  美国夏威夷大学，公共卫生学院访问学者

2006/07-2009/12  必威BETWAY官网，必威BETWAY官网，讲师

 科研成果 

主持和参与的科研项目：

1.必威BETWAY官网校自主创新基金，2662018YJ022，克氏原螯虾主要致病菌噬菌体的筛选及应用，2018.01-2020.12，30万元，在研，主持

2.湖北省科技支撑计划，2015BBA234，水产养殖动物重要病毒性疾病的诊断试剂盒研制，2016.01-2017.12，50万，参加

3.必威BETWAY官网校自主创新基金，2013PY071，团头鲂、鳜鱼、黄颡鱼主要病原性疾病快速诊断技术的研究，2013.01-2015.12，20万元，已结题，主持

4.国家自然科学基金面上项目，31172433，鲤春病毒血症病毒诱导细胞自噬的发生及其分子机理，2012.01-2015.12，62万元，已结题，主持

5.国家自然科学基金面上项目，31172325，乙型脑炎病毒激活小胶质细胞的分子机制 ，2012/01-2015/12，61万元，已结题，参加

6.国家科技支撑计划子课题，2012BAD25B06，斑点叉尾鮰健康养殖与质量安全保障技术研究，2012.01-2016.12，30万元,已结题，主持

7.必威BETWAY官网校自主创新基金，2011PY121，鲤春病毒血症病毒诱导细胞自噬的分子机理，2011.01-2012.12，15万元，已结题，主持

8.国家自然科学基金青年项目，30901118，基于SVCV/G的假型杆状病毒构建及其在鱼用疫苗研究中的应用，2010.01-2012.12，20万元，已结题，主持

9.国家自然科学基金青年科学基金项目，30901105，低磷饵料对黄颡鱼和匙吻鲟NaPi 转运载体基因表达的影响，2010.01-2012.12，20万元，已结题，参加

10.湖北省自然科学基金项目，2008CBB099，斑点叉尾鮰病毒ELISA抗体检测方法的建立。2009.01-2010.12，2万元，已结题，主持

11.教育部新教师基金项目，20070504047，斑点叉尾鮰病毒“自杀性”DNA疫苗研究。2008.01-2010.12，3.6万元，已结题，主持

发表的科研论文：

1. Wang Fang, Jiao Houqi, Liu Wanmeng, Chen Bo, Wang Yeda, Chen Buxin, Lu Yuanan, Su Jianguo, Zhang Yongan, Liu Xueqin *. The antiviral mechanism of Viperin and its splice variant in spring viremia of carp virus infected fathead minnow cells. Fish and Shellfish Immunology. 2019, 86:805-813.

2. Chen Bo, Huo Shitian, Liu Wanmeng, Wang Fang, Lu Yuanan, Xu Zhen, Liu Xueqin *. Fish-specific finTRIM FTR36 triggers IFN pathway and mediates inhibition of viral replication. Fish and Shellfish Immunology. 2019, 84: 876-884.

3. Chen Buxin, Li Chen, Wang Yeda, Lu Yuanan, Wang Fang, Liu Xueqin*. 14-3-3β/α-A interacts with glycoprotein of spring viremia of carp virus and positively affects viral entry. Fish and Shellfish Immunology.2018, 81: 438-444.

4. Wang Yeda, Zhang Hao, Lu Yuanan, Wang Fang, Liu Liyue, Liu Jingxia, Liu Xueqin*. Comparative transcriptome analysis of zebrafish (Danio rerio) brain and spleen infected with spring viremia of carp virus (SVCV). Fish and Shellfish Immunology, 2017, 69:35-45.

5. Wang Yeda, Kuang Ming, Lu Yuanan, Lin Li, Liu Xueqin*. Characterization and biological function analysis of the TRIM47 gene from common carp (Cyprinus carpio). Gene, 2017, 627:188-193.

6. Ashraf Usama, Lu Yuanan, Lin Li, Yuan Junfa, Wang Min, Liu Xueqin*. Spring viremia of carp virus: recent advances. Journal of General Virology, 2016, 97:1037-1051.

7. Wang Yeda, Li Zeming, Lu Yuanan, Hu Guangfu, Lin Li, Zeng Lingbing, Zhou Yong, Liu Xueqin*. Molecular characterization, tissue distribution and expression, and potential antiviral effects of TRIM32 in the common carp (Cyprinus carpio). International Journal of Molecular Sciences, 2016, 17(10):1693.

8. Liu Liyue^#, Zhu Bibo^#, Wu Shusheng, Lin Li, Liu Guangxin, Zhou Yang, Wang Weimin, Asim Muhammad, Yuan Junfa, Li Lijuan, Wang Min, Lu Yuanan, Wang Huanling, Cao Jianbo, Liu Xueqin*. Spring viremia of carp virus induces autophagy for necessary viral replication. Cellular Microbiology, 2015, 17(4): 595-605.

9. Wu Shusheng, Liu Liyue, Ali Zohaib, Lin Li, Yuan Junfa, Wang Min, Liu Xueqin*. MicroRNA profile analysis of epithelioma papulosum cyprini cell line before and after SVCV infection. Developmental and Comparative Immunology, 2015, 48:124-128.

10. Li Zeming, Zhang Qi, Luo Peixiao, Liu Guangxin, Wang Min, Liu Xueqin*. Monoclonal antibody against M protein of spring viremia of carp virus. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2015, 34(2):122-125.

11. Luo Peixiao, Ruan Xindi, Zhang Qi, Li Zeming, Wang Min, Liu Xueqin*. Monoclonal antibodies against G protein of spring viremia of carp virus. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2014, 33(5): 340-343.

12. Liu Liyue, Li Qin, Lin Li, Wang Min, Lu Yuanan, Wang Weimin, Yuan Junfa, Li Lijuan, Liu Xueqin*. Proteomic analysis of epithelioma papulosum cyprini cells infected with spring viraemia of carp virus. Fish and Shellfish Immunology, 2013, 35(1): 26-35.

13. Huang Fengtao, Li Qin, Cui Xiaoxian, Cao Shengbo, Xiong Chuanxi, Wang Min, Lu Yuanan, Wang Weimin, Ye Jing, Liu Xueqin *,Characterization of Spring Viremia of Carp Virus Glycoprotein Expressed by Recombinant Baculovirus, Pakistan Veterinary Journal, 2012, 32(3) :334-338

14. Huang Fengtao^#, Cao Shengbo^#, Cui Xiaoxian, Xiong Chuanxi, Wang Min, Lu Yuanan, Wang Weimin, Ye Jing, Liu Xueqin *, Efficient gene delivery into fish cells by an improved recombinant baculovirus, Journal of Virological Methods, 2011,173:294-299

15. 王方, 彭俊杰, 王业大, 刘学芹*. 鲤春病毒血症病毒核蛋白原核表达及单克隆抗体制备. 必威BETWAY官网学报, 2017, 36(03):79-85.

16. 贾路路,曾令兵,王方,彭俊杰,王业大,周勇,刘学芹*.草鱼TRIM32基因克隆表达及功能研究.水生生物学报,2017,41(04):741-747.

17. 彭俊杰,张琪,贾路路,林蠡,袁军法,曾令兵,周勇,刘学芹*.鲤疱疹病毒Ⅱ型(CyHV-2) ORF25蛋白的原核表达及单克隆抗体的制备.必威BETWAY官网学报,2017,36(02):96-101.

18. 罗培骁, 张琪, 王敏, 刘学芹*. 鲤春病毒血症病毒G蛋白的原核表达及多克隆抗体的制备. 水生态学杂志, 2014, 35(4):81-86.

授权和申请专利：

1. 刘学芹,李泽明,张琪,王业大,袁军法,贾路路,吴术盛,彭俊杰,分离的鲤抗病毒天然免疫蛋白TRIM32及抗病毒活性, ZL201510027522.5,2017.12.19,

2. 刘学芹, 张琪,李泽明,罗培骁,彭俊杰,贾路路,王业大,抗斑点叉尾鮰病毒囊膜蛋白ORF46的单克隆抗体及其应用,2018.1.12,中国, ZL201510003012.4

3. 刘学芹, 刘广鑫, 林蠡, 袁军法, 李泽明, 柳力月, 罗培骁.一种鳜鱼传染性脾肾坏死病毒的LAMP检测方法，ZL 2014101182564,2016.1.6

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